What is Hunter Syndrome?
- Hunter syndrome, also known as mucopolysaccharidosis type II, or MPS 2, is a rare, hereditary metabolic disorder that primarily affects males; it is often severe and almost always progressive.
- In people with MPS syndrome, the iduronate-2-sulfatase (IDS) enzyme, which breaks down complex sugars, is missing or not working properly.
- This leads to an abnormal buildup of complex sugars in tissues throughout the body, including the brain, skeleton, joints, spinal cord, heart spleen, or liver.
- Physical symptoms include growth delay, joint stiffness and coarsening of facial features
- When severe, MPS disease can cause respiratory and cardiac problems, enlargement of the liver and spleen, and premature death.
- Hunter syndrome can also cause neurological deficits that can lead to progressive dementia and a progressive decrease in IQ points.
YOU MUST BE:
- Ages 18 or older.
- Diagnosed with Hunter Syndrome.
- Available for 8 weeks of investigational treatment.
- Willing to discontinue standard enzyme replacement therapy and switch to AGT-182 for the duration of their participation in the clinical trial.
Inquire about the